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Biography
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Date
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Role
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2011-
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Director of Postgraduate Studies, Department of Chemical Engineering, Imperial College London
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2009-
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Professor of Biofluid Mechanics, Department of Chemical Engineering, Imperial College London |
2005-2009
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Reader in Biofluid Mechanics, Department of Chemical Engineering, Imperial College London |
2003-2005
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Senior Lecturer, Department of Chemical Engineering, Imperial College London |
1998-2003
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Lecturer, Department of Chemical Engineering, Imperial College London |
1991
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PhD in Mechanical Engineering , City University, London, UK, Thesis Title: “Numerical Analysis of Blood Flow in 3-D Arterial Bifurcations” |
| 1987 |
MSc in Thermo-Fluids Engineering , Dalian University of Science and Technology, Dalian, China, Thesis Title: “Numerical Simulation of the Working Processes of an Internal Combustion Engine” |
Research Interests
My mainstream research activities are in the field of biomedical engineering, with a special focus on fluid mechanics and transport processes in biological and physiological systems. Current research in this area includes (i) studies of flow and mechanical stresses in aortic aneurysms with an aim to develop a reliable predictive tool for aneurysm rupture on an individual patient basis, (ii) fluid/solid interaction in arteries with plaques, (iii) transitional and turbulent flow phenomena in stenosed arteries, (iv) mass transport through arterial walls, and (v) flow in realistic coronary arteries. These studies are of great importance since they will lead to better understanding of the flow characteristics and biomechanical conditions in healthy and diseased arteries. This will assist the understanding of the relationships between haemodynamics and arterial disease, and help to identify the risk predictors for potentially fatal events, such as aneurysm rupture, thromboembolism, stroke and heart attack. One of the major objectives of these studies is to develop reliable predictive tools that may assist diagnosis and surgical decision making.
In parallel to these activities, I am embarking on a new and exciting area that combines biomechanics with tissue engineering. Newly initiated research in this field includes (i) fluid dynamics and mass transport in microgravity bioreactors, (ii) tissue engineering of blood vessels, and (iii) modelling of mass transfer in 3-D perfused bone marrow culture system. The significance of this research is to gain insights into the fluid dynamic and mass transfer processes inside bioreactor systems, in order to optimise the design and operating conditions to suit the growth of different types of cells and tissues.
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