Sensorimotor Integration
How do we control our speed while moving in the environment? Is our perception of the outside affected by our movement? Studies on people running on treadmills have shown that our perception of the outside world is altered by running in such an unnatural environment. We are trying to understand the neural basis for this shift in perception.
I am currently using behavioral psychophysics to study the effect of self-motion on the perception of speed. In another study I will be looking at how control of speed is affected by the visual surround.more information
Models of Neural Coding
Reconstructing models using unbiased stimuli: I record extra-cellular neural activity from visual areas, while showing the animal a random white noise stimulus.
Novel stimuli to build neural models: Using plaid stimulus, we analyse the processing of 2D motion information by the blowfly visual system. We build neural models that describe the output of the neurons.more information
Education
PhD (Computational Neuroscience), Imperial College London, UK, 2006-present
MSc (Engineering And Physical Sciences in Medicine), Imperial College London, UK, 2004-2005
B Tech & MTech (Material Science), IIT Bombay , India, UK, 1999-2004
Publications
A H Habib and A Saleem, C V Tomy & D Bahadur, Structural Electronic and Magnetic Properties of Sr(2-x)BaxFeMoO6 (0 < x < 2), Journal of Applied Physics, 97, 10A906 (2005)
A Saleem (2004) Study of Double Perovskite Systems for Magnetoresistive Applications, Dual Degree Thesis, Indian Institute of Technology, Bombay
Conferences Abstracts & Workshops
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A Saleem, H G Krapp and S R Schultz (2007), Pattern motion selectivity in fly H1 is similar to primate MT, IBRO World Congress, Melbourne, Australia
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A Saleem, H G Krapp and S R Schultz (2007), Space-Time Spike Triggered Covariance analysis of Fly Motion Sensitive Neuron, Annual Meeting, British Neuroscience Asso., Harrogate, UK
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M O Franz, J H Macke, A Saleem, S R Schultz (2007), Implicit Weiner Series for Estimating Nonlinear Receptive Fields, 31st Gottingen Neurobiology Conf., Gottingen, Germany
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M V Nikitchenko, A Saleem, C A Hollweg and C D Brody (2007), Examining the perception of temporal interval Sequences using different stimulus and response modalities, Cosyne 2007, Salt Lake City, Utah
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Participated at "The Autumn School for Cognitive Neuroscience" at Oxford, Sept 25 -28, 2006
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Participated at "Neural Spike Train Analysis Workshop" at Newcastle, Aug 28 - Sept 8, 2006
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A Saleem and S R Schultz (2006) Subspace Spike Triggered Covariance Analysis, CNS 2006, Edinburgh, UK
Scholarships & Awards
Scholarship, Trustees of the Gatsby Charitable Foundation towards the project "Recalibration of the population code for self-motion in the alert mouse cortex", 2005
Scholarship, Department of Bioengineering Studentship, 2005
Scholorship, Overseas Research Studentship, 2006
Travel Award, Guarantors of Brain (Journal), 2007
Neuroscience Research Experience
Neural Coding of Motion by Visual Systems
PhD Thesis (Feb 2006 onwards)
Advisor: Dr. Simon Schultz , Department of Bioengineering, Imperial College, London
The aim of the project is to assess the effect of visual information on the neural activity underlying locomotion, and correspondingly the effect of motor activity on visual information processing. For the purpose of the project we will build a rig such that we can record from the cortex of a mouse while it is running on a treadmill. We will also simultaneously show it a whole field optical flow pattern. Using a multielectrode array we plan to record activity from a population of neurons to study the coding in the visual cortex with and without the application of the treadmill. A similar study will be carried out in the motor cortex to study the effect of visual flow patterns.
Perception of temporal patterns
Research Project (Nov 2005 - February 2006)
Advisor: Dr. Carlos Brody , Cold Spring Harbor Research Laboratory, New York
How is time represented in the brain? And how are they recognized? These are wide open, crucially important, but little studied questions. This project is trying to use psychophysics experiments to get some insight into the possible mechanisms of perception of temporal patterns. We particularly interested in defining rhythm in a pattern, which strongly effects perception.
Spatio-temporal STC analysis of the H1 neuron in the fly visual system
Graduate Dissertation (March 2005 - September 2005)
Advisor: Dr. Simon Schultz , Department of Bioengineering, Imperial College, London
The project aimed at using the Spike Triggered Covariance (STC) analysis to compare the motion sensitive neurons in the mammalian cortex and the fly. The work has involved setting up the rig to conduct experiments, including building and acquiring new equipment. I have also written code to run the stimuli, interface the equipment, analyse the results obtained from recordings using STC and also compare them with existing models.
Other Experience
Graduate Dissertation (May 2003 - June 2004)
Advisors: Prof. D. Bahadur, Department of Metallurgical Engg and Materials Science, IIT Bombay
Prof. C.V. Tomy, Department of Physics, IIT Bombay
Title: "Study of Double Perovskite Systems for Magnetoresistive Applications"
Research Internship (May 2002 - July 2002)
Advisor: Prof. Arun K. Tiwari, Director, Care Foundation, Care Hospital, Hyderabad
Title: "Characterisation of Titanium Clips used as surgical sutures in Laparoscopic Surgery"
Training Internship (May 2001- June 2001)
Advisor: Dr. K. B hanu Shankara Rao, Head, Mechanical Metallurgy Division, IGCAR, Kalpakkam
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